Arfgap domain
WebThe ArfGAP family, which includes 31 human ArfGAP-domain containing proteins, is divided into 10 subfamilies based on domain structure and sequence similarity. The … Web1 nov 2014 · Eukaryotic cells express numerous ArfGAPs (ADP-ribosylation factor GTPase-activating proteins). There is increasing knowledge about the function of the brain-specific protein ADAP1 [ArfGAP with dual pleckstrin homology (PH) domain] as well as about its biochemical properties. The ADAP subfamily, als …
Arfgap domain
Did you know?
WebThe ArfGAP Glo3 is required for coat protein I vesicle generation in the Golgi-endoplasmic reticulum (ER) ... Arf1. In this study, we characterized functional domains of the ArfGAP Glo3 and identified an interaction i … The GAP domain and the SNARE, coatomer and cargo interaction region of the ArfGAP2/3 Glo3 are sufficient for Glo3 function ... Web29 feb 2012 · During the vesicular trafficking process, cellular membranes undergo dynamic morphological changes, in particular at the vesicle generation and fusion steps. Changes in membrane shape are regulated by small GTPases, coat proteins and other accessory proteins, such as BAR domain-containing proteins. In addition, membrane deformation …
Web15 giu 2006 · All known ArfGAPs contain the ArfGAP domain, which executes the ArfGAP catalytic activity, but the amino-acid sequences in the rest of molecules are different from each other. When the non-catalytic C-terminal portions of Glo3p and Gcs1p were exchanged, their effects on arf1-16 were also switched, suggesting that this region is … WebARAP1:ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Gene - OMIM - HGNC] Variant type: single nucleotide variant Cytogenetic location: 11q13.4 Genomic location: Chr11: 72693327 (on Assembly GRCh38) Chr11: 72404372 (on Assembly GRCh37) Preferred name:
WebCrystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta. EMBO J. 1999; 18: 6890-8; ... Crystal Structure of mutant S554D for ArfGAP and ANK repeat domain of ACAP1: 4f6r: Tubulin:Stathmin-like domain complex: 4g8k: Intact sensor domain of human RNase L in the inactive signaling state: WebThe GAP Domain and the SNARE, Coatomer and Cargo Interaction Region of the ArfGAP2/3 Glo3 are Sufficient for Glo3 Function . × Close Log In. Log in with Facebook Log in with Google. or. Email. Password. Remember me on this computer. or reset password. Enter the email address you signed up with and we'll email you a reset ...
WebArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1) The ArfGAPs are a family of multidomain proteins with a common catalytic domain that promotes the hydrolysis of GTP bound to Arf, thereby inactivating Arf signaling. ASAP-subfamily GAPs include three members: ASAP1, ASAP2, ASAP3.
Web9 gen 2012 · This family comprises four ubiquitous members, including human ARAP-1, −2 and −3, and mouse ARAP-3. These multidomain proteins contain a SAM (sterile α-motif) domain, five PH domains, an ArfGAP domain, ankyrin repeats, a RhoGAP domain and an RA domain (Krugmann et al., 2002; Miura et al., 2002; I et al., 2004). phicomm m1 softwareWebThe encoded protein contains an N-terminal GTPase-like domain, a pleckstrin homology domain, an ArfGAP domain and several C-terminal ankryn repeat domains. [provided by RefSeq, Apr 2024] NCBI Gene. Contents. 1 Names and Identifiers Expand this section. 2 Related Genes Expand this section. 3 Proteins Expand this section. phicomm psg1218WebThe SCOP classification for the ArfGap/RecO-like zinc finger superfamily including the families contained in it. Additional information provided includes InterPro annotation (if … phicomm_n1 wifi密码Web21 mar 2024 · Entrez Gene Summary for ARFGAP3 Gene. The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and … phicomm non camera smartphonephicomm non camera phoneWeb15 mag 2016 · Domain structure of GIT and PIX proteins, including alternative splicing isoforms. GIT1 and GIT2 share the N-terminal ArfGAP domain, three ankyrin repeats (Ank), the Spa2 homology domain (SHD) – as indicated with two Spa2-like repeats – a coiled-coil (CC) dimerization domain and the C-terminal focal adhesion-targeting (FAT) domain. phicomm psg1218 rev.aWeb29 mar 2024 · The BAR domain of the Arf GTPase-activating protein ASAP1 directly binds actin filaments. Integrative analysis of genomic amplification-dependent expression and … phicomm psg1218 bx